Insanely Bad Teeth and More Incredible Mutations

2. Really Really Bad Teeth (Part II)

The name of this genetic condition says it all: amelogenesis imperfecta. In this case, imperfect is quite the understatement. There are 14 different variations of this disease, each of which can cause have its own strange effect on the development of the teeth. From thin, soft, or pitted tooth enamel to small, malformed incisors to totally discolored choppers, this disorder can really ruin a smile. Unfortunately, the condition is autosomal dominant, which means that if even one parent has the gene, the children will be affected too.

A PERSON WITH AMELIOGENESIS IMPERFECTA

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On the bright side, though, it’s rather rare and only affects an estimated 1 in 14,000 people in the U.S. For amelogenesis imperfecta, bonded restorations is often the treatment option of choice, but the complexity of the disorder calls for an interdisciplinary approach to the overall treatment plan to improve function and aesthetics. Whichever path is chosen, regular trips to the dentist (or dental surgeon!) are a must.

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